9H-Pyrano[2,3-f]-1,4-benzodioxin-9-one,2,3-dihydro-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-5-methoxy-,(2R,3R)-rel- - Names and Identifiers
Name | Cleomiscosin A
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Synonyms | NSC 346197 cleomiscosin A Cleomiscosin A (2R,3R)-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-5-methoxy-2,3-dihydropyrano[3,2-h][1,4]benzodioxin-9-one (2R,3R)-rel-2,3-Dihydro-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-5-methoxy-9H-pyrano[2,3-f]-1,4-benzodioxin-9-one 9H-Pyrano[2,3-f]-1,4-benzodioxin-9-one,2,3-dihydro-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-5-methoxy-,(2R,3R)-rel-
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CAS | 76948-72-6
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9H-Pyrano[2,3-f]-1,4-benzodioxin-9-one,2,3-dihydro-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-5-methoxy-,(2R,3R)-rel- - Physico-chemical Properties
Molecular Formula | C20H18O8
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Molar Mass | 386.35 |
Density | 1.403 |
Melting Point | 245-247℃ |
Boling Point | 632.7±55.0 °C(Predicted) |
Specific Rotation(α) | +2.5 (c, 0.07 in MeOH). 0 (c.0.5 in MeOH) |
Solubility | Acetonitrile (Slightly, Heated), Methanol (Slightly), Pyridine (Slightly) |
Appearance | Solid |
Color | White to Off-White |
pKa | 9.65±0.35(Predicted) |
Storage Condition | -20°C Freezer, Under inert atmosphere |
Use | Phosphodiesterase inhibitor |
9H-Pyrano[2,3-f]-1,4-benzodioxin-9-one,2,3-dihydro-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-5-methoxy-,(2R,3R)-rel- - Introduction
Cleomiscosin A (Cleomiscosin A) is A natural lignans, mainly found in day lily. Its chemical structure is a hydroxy coumarin compound. Cleomiscosin A is A yellow crystal with A bitter taste and medicinal value.
Cleomiscosin A has many applications in the field of traditional Chinese medicine. It is used as an irritant and analgesic drug, and is considered to have a therapeutic effect on various diseases, such as tuberculosis, cough, bronchitis, etc. In addition, Cleomiscosin A is also used as an ingredient in cosmetics, which has antioxidant and anti-aging effects.
The method of preparing Cleomiscosin A is generally extracted from day lily. First of all, the day Lily is added to the appropriate amount of solvent, the commonly used solvents are methanol, ethanol and so on. Then extraction and concentration are carried out, and finally pure Cleomiscosin A is obtained.
Cleomiscosin A is generally considered safe at appropriate doses. However, excessive use may cause some adverse reactions, such as gastrointestinal discomfort, dizziness, nausea, etc. Therefore, in the use of Cleomiscosin A should follow the principle of appropriate use, and under the guidance of A doctor or professional. At the same time, the use of the substance should be avoided for individuals allergic or people allergic to lignans.
Last Update:2024-04-09 21:11:58